Pfizer Postdoc Fellow in Cambridge, Massachusetts

About Pfizer

A career at Pfizer offers opportunity, ownership and impact.All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Role Description

We seek a driven and accomplished postdoctoral fellow to join the Molecular Design, Profiling and Production (MDPP) group within the BioMedicine Design (BMD) unit of Pfizer's Worldwide R&D (WRD) division in Cambridge, MA. The successful candidate will collaborate with colleagues from BMD and Internal Medicine (IM) research unit to study target biology in anorexia-cachexia syndrome. The successful candidate will carry out studies to validate potential functional targets and pursue novel targets identification related to anorexia-cachexia by applying a suite of molecular and cellular technologies. Additionally, this person will perform experiments to elucidate the signaling pathway underlying target activation.

Responsibilities

Work independently and as part of teams to conceive, design, execute, analyze, and interpret experiments for target identification, validation and pathway analysis. Contribute intellectually and at the bench to carry out studies of mass spec-based proteomics target identification, and pathway analysis. Apply genetic and pharmacologic approaches to validate potential targets related to cachexia/anorexia. This may include CRISPR, shRNA, viral vector delivery, transfection, antibodies, array based and other pharmacologic approaches to modulate targets. Present research results and methodologies at meetings with immediate supervisor and/or project leader, and at meetings with members of the project team as appropriate.

Qualifications

Ph.D. in biochemistry, cell biology, or molecular biology (or a comparable biological science) with a track record of scientific accomplishment as exemplified by scientific publications.Experience in applying mass spec-based proteomics technologies in target identification, validation and pathway analysis. *Experience with bioinformatics software for data analysis and interpretation.Demonstrated proficiency and experience in basic molecular and biochemical techniques, such as cell culture, RNA/protein extraction, Western blot, ELISA, etc.*The candidate should be highly-motivated and able to work as a team player in a highly interactive and multi-disciplinary research environment.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Postdoc Fellow Cambridge, Massachusetts 1053157-1852