Pfizer Senior Scientist, Synthetic Chemistry in Groton, Connecticut
We are seeking creative, enthusiastic, and highly motivated synthetic chemists to join our Pfizer Global Research and development laboratories based in Groton, CT. As part of a medicinal chemistry team, the successful applicants will contribute through innovative synthetic chemistry to the delivery of clinical candidates aligned against portfolio strategy.
Contribute to the development and enablement of a coherent synthesis strategy associated to the project: understand the goal and medicinal chemistry strategy of the project and, as part of a synthesis team, positively and proactively influence and reduce to practice the strategy through development of innovative chemistry tailored to project needs.
Development and enablement of versatile and modular synthetic routes compatible with rapid analog synthesis.
Validation of these synthesis routes through reduction to practice via the synthesis of prototype molecules.
Learn design principals and enable synthetic methodology to allow compound to achieve design objectives.
Liaise with outsourcing point of contact in the team to ensure optimum transfer of the enabled chemistry to allow for rapid analog synthesis externally. Also, when applicable, be able to manage a pool of remotely located chemists assigned to analog synthesis.
Develop scalable routes of preclinical candidates.
Build effective partnerships with other lines, in particular analytical, technology, pharmaceutical sciences and process chemistry groups.
Publish and present research internally and externally to Pfizer.
- Doctoral level degree.
Training and Experience:
Proven track record of creative thinking and consistent delivery as demonstrated by publication/presentation records.
Dual expertise in methodology development and successfully completed multistep syntheses.
Expertise in either organometallic chemistry, catalysis, or chemical biology is recommended.
Postdoctoral experience strongly recommended.
Previous experience in mentoring and development of junior scientists or students is a plus.
Highly skilled synthetic chemist in the area of methodology development and multistep synthesis.
Strong knowledge of techniques related to purification and characterization of organic compounds.
Effective communication and leadership skills; must be able to interact effectively within a multidisciplinary team of colleagues.
Comfortable working in a highly innovative environment and can effectively cope with change. -- Responds well to scientific challenge and applies significant rigor to their own work.
Will scientifically challenge others in their group in a constructive manner and demonstrate exceptional team working skills (e.g. approachable and collaborative) to ensure the group as a whole is successful.
Most astute reader of chemical literature.
Requires the ability to carry out experimental organic chemistry in a standard chemistry laboratory.
Additional Offer Details:
Additional Location Information: Groton, CT
Eligible for Relocation Package
Eligible for Employee Referral Bonus
EEO & Employment Eligibility
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