Pfizer Scientist Molecular Biology/Genetics in Kalamazoo, Michigan

The position of Scientist - Molecular Biology/Genetics will work as part of an interdisciplinary team to improve Pfizer's production processes through biotransformation, biocatalysis and microbial culture improvement projects.

Principal duties include enzyme engineering/evolution, high through-put screening, strain construction and improvement, pathway and metabolic engineering, and development of new molecular biology tools to accomplish these tasks.

The Bioprocess Development Group (BDG) is a group of 25 highly engaged scientists that apply state of the art genetic, microbiological, engineering and analytical technology to support the lowest cost production of small-molecule active pharmaceutical ingredients (API) via enzymatic and fermentation processes.

ROLE SUMMARY

The position of Scientist - Molecular Biology/Genetics will work as part of an interdisciplinary team to improve Pfizer's production processes through biotransformation, biocatalysis and microbial culture improvement projects.

Principal duties include enzyme engineering/evolution, high through-put screening, strain construction and improvement, pathway and metabolic engineering, and development of new molecular biology tools to accomplish these tasks.

The Bioprocess Development Group (BDG) is a group of 25 highly engaged scientists that apply state of the art genetic, microbiological, engineering and analytical technology to support the lowest cost production of small-molecule active pharmaceutical ingredients (API) via enzymatic and fermentation processes.

ROLE RESPONSIBILITIES

  • Improve production strains by molecular biological methods and by traditional mutagenesis and screening.

  • Identify and evolve enzymes for increased activity, specificity and selectivity.

  • Determine and understand metabolic or reaction pathways and genetically engineer those pathways for improved culture performance and/or to produce new APIs.

QUALIFICATIONS

Education:

  • BS in Molecular Biology, Biochemistry, Microbial Genetics or related fields with 2-5 years of experience

  • MS in Molecular Biology, Biochemistry, Microbial Genetics or related fields with 0-3 years of experience

Experience:

  • Experience working with genetic modification of E. coli, actinomycetes, yeasts, and/or other important industrial micro-organisms. Industrial or lab experience (non-coursework) and experience with nonconventional yeasts preferred.

Technical Skills

  • Strong knowledge of molecular genetics techniques and computer software, and operation of molecular biology related instrumentation especially with industrially relevant microorganisms.

  • Skill and working knowledge in bioinformatics, including competence in using common desktop bioinformatic apps such as DNA Star, Vector NTI, CLC Bio Main/Genomics Workbench and Geneious.

  • Ability to analyze, interpret, and communicate experimental data.

  • Strong initiative and good problem solving skills. Takes personal responsibility for own work, pushing self and others to exceed goals and deliver results.

  • Must have demonstrated communication skills, both written and oral.

  • Must be able to establish positive colleague relationships which foster collaboration and cooperation. BDG is a team-based organization. Good peer relationships are the only way to get projects done and to succeed.

  • Change agile - can effectively cope with change.

PHYSICAL/MENTAL REQUIREMENTS

Lab position: Frequent standing and walking, frequent detailed manual manipulations, and computer-based work.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

First shift position - some overtime and/or weekend work may be required.

OTHER INFORMATION

  • Not relocation eligible

  • Posting title: Scientist - Molecular Biology/Genetics

EEO Statement

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Additional Offer Details:

  • Last Date to Apply for Job: July 31, 2017

  • Grade: 04

  • Additional Location Information: Kalamazoo, MI

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.