Pfizer Senior Research Associate (Non in San Diego, California
A career at Pfizer offers opportunity, ownership and impact.
All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.
Pfizer Vaccine Research and Development seeks to discover novel vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human diseases (e.g. infectious diseases, oncology) using a variety of vaccine technology platforms combined with immunomodulatory agents.
We are seeking a Virus Purification Senior Associate Scientist to join the Early Bioprocess Development group in Vaccine Research, La Jolla, California, to develop and support virus production/purification processes at the research scale.The successful candidate will have solid knowledge and experience in virus purification and be able to independently and proactively apply this knowledge to the design and execution of experimental work, enabling progression of vaccine discovery projects from preclinical to early development. The role will encompass both preclinical reagent supply along with early process development for clinical vaccine candidates.
The successful candidate will be required to work with BSL2 infectious viruses- Including Vaccinia
Experience in one or more of the following areas is essential:
Virus and/ or protein purification using chromatographic techniques - with experience using Unicorn based FPLC systems.
Tangential flow filtration
Ultracentrifugation based purification
Additional desirable skills would include:
Virus and/ or protein characterization techniques
Virus production at bioreactor scale
Experience in safe handling of BSL2 infectious viruses - e.g. Adenovirus & Vaccinia
The candidate will be required to work with moderate supervision and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones. The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work
Roles and Responsibilities
EXPERIMENTAL/LABORATORY & RELATED WORK under daily to weekly supervision (80-90%):
Work with supervisor to define aim and a plan to achieve that aim, will then execute work following the plan (independently, if familiar with area of work, with guidance if unfamiliar).
Experimental design in consultation with supervisor, literature review, and increasing emphasis on independent design based on experience.
Will carry out on-going analysis of data generated and will identify problems. Will implement necessary changes following discussion with peers/ supervisor.
Will analyze and interpret experimental data, results and methodology used with guidance.
Will gain skills and experience to be fully conversant with the operation and validation of all items of equipment or IT needed for experimentation, data analysis, storage and data entry.
Be able to review literature and suggest/apply to technical solutions to bioprocess problems of moderate complexity
Will write-up laboratory notebooks regularly in compliance with Pfizer IP policy and GSP
Preparation of presentation materials. COMMUNICATION & Scope of Team Influence
Will have effective communication skills, both verbal and written; listens and understands well.
Will regularly communicate with supervisor and team scientists
Will regularly contribute and influence at the discipline and project team level as a team participant. Safe working and regulatory compliance
Work safely themselves and be aware of EHS practices of other colleagues in all aspects of role, including handling of BSL2 infectious viruses.
Completion of risk assessments, compliance training as required
Acts independently to maintain a safe and EHS compliant desk and workspace
A BSc in in biological sciences or Biochemical/chemical engineering with 3+ years relevant laboratory experience
An MSc in biological sciences or Biochemical/chemical engineering with relevant laboratory experience
Standard laboratory conditions - sitting, standing, primarily lab based
Ability to lift up to 30 lbs
Working with BSL2 infectious viruses
Ability to perform mathematical calculations and complex data analysis
No/ infrequent travel
Non-standard work schedule, travel or environment
Must receive and maintain required vaccinations or provide satisfactory proof of same.
SVP of Early Bioprocess Development -> Associate Research Fellow, Head of process development - LJ -> Prinicipal Scientist->Position
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
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Additional Offer Details:
Eligible for Employee Referral Bonus
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.