Pfizer Scientist, Biology (non in San Francisco, California
- We are seeking to hire an energetic and collaborative scientist with demonstrated expertise in cellular immunology, immuno-oncology, and/or cellular therapies to join our team and contribute to exciting research on allogeneic Chimeric Antigen Receptor (CAR) T cells.
Contribute to the overall advancement and success of our allogeneic CAR T cell research program through collaboration across functions and projects
Investigate and implement novel technologies to enhance the function, migration and persistence of allogeneic CAR T cell products
Stay current on the latest scientific literature relevant to cellular therapies, cellular engineering, and cellular immunology
Organize, interpret, and present results in small and large group meetings
Contribute to a dynamic, exciting culture that embraces teamwork and innovation
B.S. degree with 6+ years of experience, M.S. degree with 5+ years of experience
Candidates with prior experience in industry or a high-profile academic lab preferred
Degree in biology-related field required; degree in immunology or cell biology preferred
Prior experience in the fields of cellular immunology, immuno-oncology, and/or cellular therapies highly preferred
Preferred Technical Skills
Isolation and culturing of human and mouse immune cells from blood or primary tissues
Generation of retroviral and/or lentiviral vectors and transduction of target cells
Design and execute molecular cloning strategies (PCR, cloning, sequencing, VectorNTI or similar)
Use of gene-editing technologies such as CRISPR-Cas9 and/or TALENs
Analysis of T cell function in vitro using multicolor flow cytometry, cytokine ELISA (MSD, Luminex or similar)
DNA isolation techniques for genome and transcriptome analysis
Proficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook)
Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis
Proven ability to: manage work load andwork and think independently and creatively; design a well-controlled experiment; analyze results with a keen, critical mind; organize results and generate presentations; present results in small and large group meetings in a clear and organized manner; be an affable and energetic colleague and team player.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Must be willing to work with human blood, retroviral and HIV-derived lentiviral vectors, other viral-based vectors such as adeno-associated virus (AAV) under biosafety level 2+ guidelines. Ability to drive and access to a car helpful for travel between buildings, but not required.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
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Additional Offer Details:
Additional Location Information: South San Francisco, CA
Eligible for Employee Referral Award
A career at Pfizer offers opportunity, ownership and impact.
All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.