Pfizer Scientist: Immuno in San Francisco, California

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

We are seeking a highly motivated scientist with experience in oncology or immune-oncology research to join the cancer immunotherapy group and contribute to our ongoing efforts in the discovery and development of immune-oncology agents.

• Design in vitro/vivo experimental plans and optimize the assays for antibody drug candidate screening.

• Conduct experiments, analyze results to draw meaningful conclusions, and troubleshoot results.

• Will communicate research results to manager and the team.

• Record experimental protocols/results in detail and write technical reports for regulatory filings.

• Work in a fast-paced and highly collaborative environment within the group.

• Attend team meetings and deliver well-prepared presentations and is expected to be an active participant in discussions.

Education and Experience:

• BS in biological sciences with 6+ years' of experience, or MS with 5+ years', in pharmaceutical industry or academic setting.

• Prior experience in the fields of immune-oncology, cancer biology, and/or immunology highly preferred.

• Minimum of 2 years' of experience in cell culture, in-vitro cell functional assays, and in-vivo tumor models.

Technical Skills:

• Technical expertise with cell-based functional assays (e.g. activation, differentiation, and suppression assays of monocyte/ macrophages, T-cells, or dendritic cells, ADCC, ADCP) on the multi-color flow-cytometry and ELISA basis highly desired.

• Proficiency with mammalian cell culture techniques, immune cell isolation/differentiation from human blood, tissue processing including tumor dissociation for multi-color flow-cytometry analysis required.

• Hand-on experience with syngeneic and xenograft mouse models of cancer including tumor implantation, tumor caliper/imaging measurement, antibody drug dosing, survival analysis, and organ isolation strongly preferred.

• Ability to use appropriate software to perform analysis of data is required (Excel, GraphPad Prism, FlowJo).

• Must have excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic.

• A willingness to learn and adopt new experimental skills as needed is essential

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Colleagues who are issued an Incident Final Warning (IFW) on or after January 1, 2016, are not eligible to post and compete for a position for a period of 12-months from the date an IFW is issued.A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.