Pfizer Senior Scientist, Immune in San Francisco, California

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

We are seeking a Senior Scientist to lead an immune-oncology therapeutic program from discovery to the clinic. The position is within the Immunology and Metabolism Group at Rinat, Pfizer's biotech Research Unit in South San Francisco. Rinat specializes in antibody-based immune-oncology therapeutics. Working in collaboration with Rinat's Protein Engineering group, the candidate will champion novel immune-oncology drug development programs. They will be responsible for the day-to-day management, and long-term success, of these drug development efforts.

We are seeking candidates who:

• Have a successful track record in leading projects in immunology research or antibody drug development in oncology

• Are well-versed with the current literature and advances in the field

• Can rigorously apply in vitro and in vivo immune models to generate key decision-making datasets

• Have a track record of fruitful collaboration, preferably across multiple subject areas

• Demonstrate meticulous record-keeping skills

• Are comfortable regularly presenting data to scientists and senior leadership

An ideal candidate will also have demonstrated experience in the following areas:

• Designing and executing pre-clinical murine tumor models

• Translating mouse in vivo data to human primary cell in vivo and ex vivo assays

• A deep understanding of T cell and/or NK cell biology, and of models that interrogate and modulate cells / mediators at the innate/adaptive immune interphase.

• B.S. degree with 15+ years in industry, M.S. degree with 10+ years in industry, or PhD with 2+ years' post-doctoral training, preferably in Immunology or a related field.

• Extensive hands on experience in state of the art immunology techniques including mutli-parameter flow cytometric analysis and sorting, cytokine analysis, functional assays, imaging.

• Previous experience with tumor models is a plus.

• Previous experience with human T cells and NK cells is a plus.

• Previous experience in antibody drug discovery is a plus.

• Strong motivation with a dedicated work ethic.

• Excellent oral presentation and communication skills.

Other requirements:

Standing, walking, working in the lab, working with rodent animals.

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Colleagues who are issued an Incident Final Warning (IFW) on or after January 1, 2016, are not eligible to post and compete for a position for a period of 12-months from the date an IFW is issued.A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.