Pfizer Associate Engineer, Clinical Manufacturing in Andover, Massachusetts


The clinical manufacturing operations engineer is part of a multi-disciplinary team responsible for cGMP production of phase I/II clinical drug substance supporting the Pfizer Biotherapeutics portfolio.

Initial focus is on the start-up of a new facility in support of facility/equipment commissioning and qualification, creation of necessary cGMP documentation, and training of operations staff.

Post facility start up, the successful candidate will transition to 2nd shift to be part of a team that will be responsible for the execution of upstream mammalian and microbial processes.


  • Execute and troubleshoot upstream mammalian cell culture and microbial fermentation processes in a cGMP environment. Includes support and troubleshooting of CIP, SIP operations.

  • Lead/support tech transfer activities for new products and product changeover for operations team

  • Authorship of and execution against SOP's for upstream unit operations

  • Lead/support the creation of manufacturing batch records and other cGMP documentation

  • Data analysis and communication/collaboration with tech transfer team, development labs and quality

  • Training of operations colleagues

  • Support implementation of new technologies and equipment

  • Support investigations and audits as needed


  • BS/BA in Biotechnology, Microbiology, Cell Biology, Chemical Engineering, Biochemistry or equivalent

  • 0-2 years of experience in a laboratory or manufacturing environment


  • Knowledge of mammalian cell culture and/or microbial fermentation processes

  • Experience with operation of single use systems.

  • Experience with Production Control Systems (i.e. DeltaV), ERP Systems (i.e. Microsoft Dynamics and/or SAP) and other business systems (Document Management Systems, LIMS, Microsoft Word, Excel, etc.)

  • Ability to execute against SOP's and document entries in a compliant manner

  • Demonstrated capability to work as a team member in a matrix manufacturing team

  • Excellent oral and written communication skills

  • Ability to work under minimal supervision


  • Must be able to climb flights of stairs, and remain standing for 1-2 hours

  • Must be able to lift up to 50 lbs


  • This is a 2nd shift position, however during commissioning and start up, the candidate will work 1st shift hours. Once the facility is operational, the candidate will transition to 2nd shift.

  • Ability to work off shift (Nights and Weekends) as needed; non-routine

  • Ability to work in a clean room environment

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

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Other Job Details:

  • Last Date to Apply for Job: July 1, 2018

  • Eligible for Employee Referral Bonus: yes

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.