Pfizer Senior Scientist, Novel Delivery Technologies in Andover, Massachusetts

The incumbent candidate will bring to this laboratory-based role the requisite expertise for developing, evaluating and characterizing bioconjugates and other novel drug delivery formulations for the delivery of diverse biotherapeutic modalities including (but not limited to) protein candidate molecules, vaccines, gene medicine and cell-based therapies, and other targeted delivery strategies. This individual functions as a bioconjugation chemist and drug delivery scientist and is responsible for working in a team-based environment to meet project deadlines. The incumbent displays strong scientific and technical expertise in various aspects of analytical chemistry, organic chemistry, and protein chemistry. Incumbent must have the scientific commitment and strong desire to make impactful scientific and technical contributions within the Pharmaceutical Research & Development team and the respective project teams.

Role Responsibilities

  • Provide scientific and technical expertise in bioconjugation chemistry and analytical methods of characterization of bioconjugates

  • Hands-on experimentation towards the preparation of innovative drug delivery solutions including, but not limited to, bioconjugates composed of proteins, peptides, biopolymers and other biomolecules

  • Utilize chromatographic, biophysical and other analytical methods for characterization in order to fully understand quality attributes for early research studies

  • Manage laboratory, including care and upkeep of complex lab instrumentation, oversight of important reagent/sample inventory, and strategic scientific instrument capital planning

  • Data management, including notebook keeping, processing of data, writing reports on projects and presenting results to team members and to larger diverse audiences

Basic Qualifications

  • Ph.D. with 0-3 years relevant laboratory experience, M.S. with 3-6 years relevant experience or BS/BA with 5-8 years relevant experience

  • Subject matter expertise in bioconjugation chemistry, linkers and techniques is essential

  • Hands on experience with synthesis, purification and analysis of protein-polymer conjugates, targeted nanoparticles, antibody-drug conjugates or oligonucleotide conjugates is required

  • Analytical expertise with UPLC, FPLC, SEC, IEX, HIC, Affinity chromatography, Mass Spectrometry (TOF, MALDI), Biacore, and/or AF4-MALS is required

  • Excellent interpersonal skills and ability to work with others in a dynamic and highly collaborative environment is essential

Preferred Qualifications

  • Expertise in protein and peptide analytical and purification techniques such as SDS-PAGE, Capillary Electrophoresis, ELISA, and/or other methods is highly recommended

  • Some experience with drug delivery technologies is a plus

  • Working knowledge in chemical synthetic reactions and reagents for both small molecules and/or biopolymers is highly recommended

  • Some experience with nanoparticles or liposomes and particle characterization such as particle sizing and counting is a plus

Other Job Details:

  • Last Date to Apply for Job: April 30, 2018

  • Additional Location Information: Andover, MA

  • Eligible for Employee Referral Bonus

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.