Pfizer Senior Scientist, Novel Delivery Technologies in Andover, Massachusetts
The incumbent candidate will bring to this laboratory-based role the requisite expertise for developing, evaluating and characterizing bioconjugates and other novel drug delivery formulations for the delivery of diverse biotherapeutic modalities including (but not limited to) protein candidate molecules, vaccines, gene medicine and cell-based therapies, and other targeted delivery strategies. This individual functions as a bioconjugation chemist and drug delivery scientist and is responsible for working in a team-based environment to meet project deadlines. The incumbent displays strong scientific and technical expertise in various aspects of analytical chemistry, organic chemistry, and protein chemistry. Incumbent must have the scientific commitment and strong desire to make impactful scientific and technical contributions within the Pharmaceutical Research & Development team and the respective project teams.
Provide scientific and technical expertise in bioconjugation chemistry and analytical methods of characterization of bioconjugates
Hands-on experimentation towards the preparation of innovative drug delivery solutions including, but not limited to, bioconjugates composed of proteins, peptides, biopolymers and other biomolecules
Utilize chromatographic, biophysical and other analytical methods for characterization in order to fully understand quality attributes for early research studies
Manage laboratory, including care and upkeep of complex lab instrumentation, oversight of important reagent/sample inventory, and strategic scientific instrument capital planning
Data management, including notebook keeping, processing of data, writing reports on projects and presenting results to team members and to larger diverse audiences
Ph.D. with 0-3 years relevant laboratory experience, M.S. with 3-6 years relevant experience or BS/BA with 5-8 years relevant experience
Subject matter expertise in bioconjugation chemistry, linkers and techniques is essential
Hands on experience with synthesis, purification and analysis of protein-polymer conjugates, targeted nanoparticles, antibody-drug conjugates or oligonucleotide conjugates is required
Analytical expertise with UPLC, FPLC, SEC, IEX, HIC, Affinity chromatography, Mass Spectrometry (TOF, MALDI), Biacore, and/or AF4-MALS is required
Excellent interpersonal skills and ability to work with others in a dynamic and highly collaborative environment is essential
Expertise in protein and peptide analytical and purification techniques such as SDS-PAGE, Capillary Electrophoresis, ELISA, and/or other methods is highly recommended
Some experience with drug delivery technologies is a plus
Working knowledge in chemical synthetic reactions and reagents for both small molecules and/or biopolymers is highly recommended
Some experience with nanoparticles or liposomes and particle characterization such as particle sizing and counting is a plus
Other Job Details:
Last Date to Apply for Job: April 30, 2018
Additional Location Information: Andover, MA
Eligible for Employee Referral Bonus
EEO & Employment Eligibility
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