Pfizer Sr. Associate Scientist, Culture Process Development in Andover, Massachusetts


A Senior Associate Scientist (R2) position is available in the Culture Process Development group of Bioprocess R&D. The successful applicant will join a team of scientists and engineers focused on developing and optimizing mammalian cell culture processes for recombinant proteins and biologics for early- and late-phase human clinical trials. In this role, the candidate will be responsible for designing and executing mammalian cell bioreactor experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes that produce therapeutic proteins with the appropriate product quality to treat human diseases. The work will also involve working with pilot scale, commercial and clinical production facilities to ensure accurate technology transfer and successful large-scale production. The candidate may also be involved in cutting edge technology development projects that seek to discover broadly applicable methods to intensify mammalian cell culture.


  • Responsible for execution of bioreactor and shake flasks experiments in an effort to design manufacturing processes for mammalian cell lines producing therapeutic biological molecules of interest.

  • Contributes to discussions in lab and project team meetings on design of experiments (bioreactor and shake flask) and interpretation of experimental data.

  • Contributes to safe, efficient, effective and harmonious lab environment, ensures appropriate cleanliness and status/ operability of shared or assigned lab space or equipment; strong lab citizen and collaborative team player; approaches the job with energy and commitment; demonstrates initiative.

  • Ensures effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks and internal technical reports; presents data/ strategy to scientists and management in appropriate internal and external venues (technical meetings, project team meetings, conferences) as appropriate.


  • BS/BA with 2-4 years' experience, or MS with 0-2 year experience in Biotechnology, Microbiology, Cell Biology, Chemical Engineering, Biochemistry or equivalent.

  • Knowledge of drug development processes for progression of a biological candidate.

  • Practical knowledge of mammalian cell culture and cell physiology/metabolism

  • Practical knowledge of mammalian expression systems

  • Experience developing commercially relevant processes to produce pharmacologically active proteins

  • Experience in supporting the scale-up and technology transfer to pilot/commercial scales

  • Knowledge of GLP/GMP practices

  • Excellent oral and written communication skills

  • Extreme attention to detail

  • Experience with technical report writing.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Sunshine Act

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Other Job Details:

  • Last Date to Apply for Job: May 15, 2018

  • Eligible for Employee Referral Bonus: yes

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.