Pfizer Biomarker Laboratory Sr. Scientist (R4) in Groton, Connecticut
The major responsibilities of the candidate will be to support the portfolio with the development and implementation of preclinical and clinical biomarkers enabling increased CIS (Confidence in Safety) and early safety-based candidate selection. The biomarker activities will support global biomarker functions.
Biomarker Laboratory scientists are responsible for laboratory-based activities to support the goals of DSRD, WRD and BUs.
They will demonstrate technical competency in areas such as immunoassay and multi-plex techniques (ELISA, Bioplex/Luminex, and Mesoscale technologies), molecular biology, mRNA/miRNA evaluations, flow cytometry or other laboratory-based science.
They will generate and evaluate data from in-vitro and in-vivo experiments under GLP and/or non- GLP experimental conditions.
They will contribute to timely methodology development/validation for new biomarkers, contribute to technology development and writing of validation reports where appropriate.
They will process samples from studies related to animal models, nonclinical target and/or compound studies with safety and/or efficacy endpoints, general toxicology, carcinogenicity, and mechanistic studies, and human clinical samples as appropriate.
They will prepare reports of laboratory findings and assist in the communication of results within and external to DSRD.
BS/MS with 7 Years of relevant experience in biomarker science OR PhD in biology or related field and related experience
Experience in computer information systems, spreadsheet applications, or other data management systems
Prior experience in a particular technical laboratory function (i.e. immunoassay and multi-plex techniques (ELISA, Bioplex/Luminex, and Mesoscale technologies), molecular biology, mass spectrometry flow cytometry, etc.) is needed
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