Pfizer Director, Immunosuppression in United States
Pfizer Cancer Immunology Discovery (CID) is the South San Francisco unit within the Oncology division of Pfizer Worldwide Research & Development. CID is dedicated to developing new protein therapeutics to improve human life by redirecting the immune system against cancer. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics. Cooperation and support for a high level of scientific freedom is encouraged in this small biotech-like environment to find the best answers to biological questions, with the benefit of large pharma resources.
We are seeking to hire the head of our tumor microenvironment program. The candidate should be a highly motivated and accomplished scientist with demonstrated expertise in understanding and modulating the tumor microenvironment. This position is responsible for defining the strategy for Pfizer's large molecule IO intervention targeting the immunosuppressive tumor microenvironment, which includes establishing and implementing new programs to target inhibitory cell types such as tumor infiltrating myeloid cells and suppressive stromal cells. The successful development of new innovative therapeutics will require close collaboration with a variety of inter-disciplinary colleagues including clinicians, protein engineers, and target identification and biomarker researchers.
Contribute to overall strategy for cancer immunology at CID and defining a strategy for large molecule IO intervention targeting the immunosuppressive tumor microenvironment
Supervise and mentor several teams committed to delivering IND-enabling packages over the next 2-4 years
Collaborate with immuno-oncology, protein engineering, computational biology, and clinical development groups to pursue the most promising drug candidates through clinical trials.
Supervise a group conducting target validation for new targets
Participate in collaboration on novel IO targets with internal and external collaborators.
Lead the latest scientific advancements in the field as a thought leader and spokesperson for Pfizer IO research, especially in the field of the tumor microenvironment
Contribute to a culture that embraces continuous learning, development, and collaboration
PhD with 10-15 years post-doctoral training with significant relevant experience in cancer immunotherapy including myeloid biology and/or tumor stroma biology
Experience managing a large team is essential
Knowledge of cellular and molecular immunology
Ability to design and supervise all aspects of in vitro and in vivo cancer immunotherapy models
Track record of publications and innovation
Ability to design and deliver novel solutions to challenging problems
Pro-active attitude and strong desire to discover novel biology and potential new drugs
Strong oral presentation and communication skills
Ability to perform complex data analysis
Ability to analyze and interpret work published in the field and use it to place our work in context
- Industry experience, including regulatory agency interaction is highly desired, including experience of target validation and candidate selection
- Role requires travel
EEO & Employment Eligibility
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Other Job Details:
Additional Location Information: South San Francisco, CA
Eligible for Relocation Package
Eligible for Employee Referral Bonus
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.